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While existing treatments for AUD and SUDs are often limited by regulatory restrictions and stigma, GLP-1RAs may benefit from their established approval for metabolic disorders

Common side effects may include: Nausea and vomiting Diarrhea or constipation Abdominal pain or bloating Decreased appetite (this is the intended effect, but can feel intense initially) Most patients find that these side effects are mild and tend to decrease as the body adjusts to the medication

Numakawa T, Kajihara R (2023) Involvement of brain-derived neurotrophic factor signaling in the pathogenesis of stress-related brain diseases

Keywords: GLP-1 receptor agonists