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[Abstract] Changes in ATP levels in cells were detected using the luciferase method after 24 h of MK2206 and 6PPDQ treatments on A549 and H1299 cells
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One of these studies demonstrated a 1.7-fold higher recovery of toxic metabolites in those with Gilberts syndrome compared to controls [33], although a larger study only found a higher rate of recovery of toxic metabolites in those patients stratified by having the lowest UGT activity [28]
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