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Several factors facilitate ALF progression, including viral infections, improper medications, immoderate alcohol consumption, and Ischemia-reperfusion injury (IRI) (James et al., 2003
NADPH is used as a cofactor by glutathione reductase (GR) to reduce oxidized glutathione (GSSG2GSH), and likewise by thioredoxin reductase to reduce oxidized thioredoxin
You can learn more in our guide on how to check for a vitamin deficiency
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