Hormones that control appetite begin to change, making you feel hungrier over time
Monthly during use: Self-examine all moles using the ABCDE criteria: - A symmetry: One half does not match the other - B order: Edges are irregular, ragged, or blurred - C olor: Uneven color with shades of brown, black, red, white, or blue - D iameter: Larger than 6 mm (the size of a pencil eraser) - E volving: Any change in size, shape, color, elevation, or any new symptom (bleeding, itching, crusting) 3

Call your healthcare professional immediately or seek emergency medical attention if you develop unusual or serious symptoms after taking Linzess, such as: Severe abdominal pain Bloody or black stools Dizziness or fainting Signs of dehydration (excessive thirst, dry mouth, sunken eyes, fast heartbeat) Severe allergic reaction (skin rash, hives, itching, swelling of the lips, tongue, or throat, difficulty breathing) Rare but serious risks of taking Linzess include: Dehydration: Linzess should never be given to children younger than 2 years of age because it can cause life-threatening serious dehydration (loss of body fluids) in very young children
Benefits: Dual Action: Targets both GIP and GLP-1 receptors for enhanced effectiveness