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However, it is worth noting that another medication in the incretin-based therapy class metformin is well-established to reduce vitamin B12 absorption in some patients through effects on calcium-dependent ileal uptake mechanisms
B12 injections are especially helpful for several specific groups: Vegans and Vegetarians: Those who don't consume animal products might struggle to get enough B12 from their diet
This may help as you wont use it as frequently as your dominant arm and may not notice the soreness as much
No head-to-head clinical trials have compared compounded semaglutide with B12 against standard formulations for weight loss efficacy
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