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Animal studies have demonstrated that GLP-1 receptors are present in the mesolimbic reward pathway, including the ventral tegmental area and nucleus accumbensbrain regions implicated in food reward and addictive behaviors
Polyphenols selectively reverse early-life stress-induced behavioural, neurochemical and microbiota changes in the rat
The mechanism involves both central nervous system pathways in the hypothalamus and peripheral pathways through melanocortin receptors in spinal cord and penile tissue
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