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Your Body Defends Fat Stores During Weight Loss When calories drop, your body activates survival mechanisms to conserve energy and fat stores: Hunger hormone (ghrelin) increases Satiety (feeling full) hormones (leptin, PYY, CCK) decrease Metabolism slows Cravings intensify The brain becomes hyper-focused on food These are not psychological weaknesses they are normal physiology
Di Lorenzo, N
Global obesity spending reached nearly $24bn in 2023, an over sevenfold growth in value in just three years, driven by the advent of new agents, and from 2024 onwards the market is forecasted to accelerate rapidly, with a possible 24-27% CAGR to 2028, and a potential value of up to $131bn by 2028, according to the IQVIA Institutes Global Use of Medicines 2024 report 4
doi: 10.1016/j.ejphar.2012.12.012 143 McCleanPLJalewaJHolscherC
