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Yoo, T.H

4.6 Ophthalmological effects 4.6.1 Glaucoma GLP-1R agonists exhibit anti-inflammatory and neuroprotective properties, suggesting they could also be beneficial in neurodegenerative diseases (73)

for example, the intestinal microbiota composition changes in response to manipulation of estrogen receptor (ER-) [103], and in response to hormonal imbalance, such as in polycystic ovary syndrome (PCOS), or pregnancy [104, 105]

While much has been published on cellular expression of GPCRs, including the GLP-1R, when evaluating the validity of such data it is key to consider the methodologies applied [e.g., immunohistochemistry (IHC), in situ hybridization (ISH), polymerase chain reaction (PCR), in situ ligand binding (ISBL)]