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Progressive weight loss throughout the 13-week treatment period, with no evidence of plateauing

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2025 NMA (29 RCTs, n=1,476): Reduced body weight by MD 3.44 kg, BMI 2.05, & waist 4.39 cm vs

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Have complex or high-risk medical conditions - Patients with unstable cardiovascular disease, advanced kidney disease, recurrent pancreatitis, gastroparesis, or complex medication regimens may require closer in-person monitoring

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Established adverse effects associated with GLP-1 receptor agonists were also evident across the dataset

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