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Animals and treatment C57BL/6J mice (male, weight: 20-25g, age: 78 weeks) housed in specific pathogen-free environment under a cycle of 12 h light and dark with food and water ad libitum
A large number of clinical studies have shown that this loss of appetite caused by treatment with semaglutide or tirzepatide is associated with a significant decrease in body weight in people who suffer from obesity
1), and also acts on receptors in pancreatic -cells, myocytes in the sinoatrial node, and Brunners glands in the duodenum(Knudsen et al 2014)
Second, repeated migraine attacks are accompanied by ictal oxidative stress and transient antioxidant consumption [39]
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