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The most common side effects are gastrointestinal, including nausea, vomiting, diarrhoea, and constipationsymptoms that can be particularly problematic in Parkinson's patients who often already experience autonomic dysfunction and gastroparesis

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The GIP component appears to enhance insulin sensitivity in fat tissue, improve lipid metabolism, and potentially increase energy expenditure in ways that pure GLP-1 agonists cannot match

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