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GSH is also involved in the neutralization of lipid aldehydes (4-HNE, MDA) generated by mitochondrial lipid peroxidation
It is a reason to prefer freshly prepared material over stored solutions in any copper-containing blend, and a reason that stability data generated on single compounds should not be assumed to transfer to blends
For mild deficiencies, you may need 2-3 injections over several weeks to notice the impact
This process is initiated by Fe 2+ -catalyzed lipid peroxidation process through non-enzymatic (Fenton reaction) and enzymatic mechanisms (lipoxygenase) [221]
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