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miR-195 reduces age-related blood-brain barrier leakage caused by thrombospondin-1-mediated selective autophagy
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All patient samples were collected in accordance with the principles of the Declaration of Helsinki and with the approval of the Institutional Review Boards of Avicenne Hospital and DFCI
However, such newly formed blood vessels are leaky because of their discontinuous endothelium, along with the obstruction of lymphatic drainage, producing vascular hyperpermeability and enhanced permeation [41]
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