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Heavy weightlifting, especially exercises that involve a Valsalva maneuver (holding breath against a closed glottis), dramatically spikes intra-abdominal pressure

Adding tesamorelin to a retatrutide protocol could theoretically accelerate visceral fat reduction beyond what retatrutide achieves alone

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This approach takes longer to reach full therapeutic doses but can be particularly valuable for people who had severe reactions to GLP-1 medications at standard starting doses