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The distinguishing features of infection versus simple inflammation are progressive worsening beyond 48 hours, spreading redness with clear borders that expands outward, red streaks radiating from the injection site (indicating lymphangitis), warmth that increases rather than decreases over time, pus or cloudy discharge from the site, and fever above 100.4 degrees Fahrenheit (38 degrees Celsius)
Kellerer, M., et al., Effect of once-weekly semaglutide versus thrice-daily insulin aspart, both as add-on to metformin and optimized insulin glargine treatment in participants with type 2 diabetes (SUSTAIN 11): A randomized, open-label, multinational, phase 3b trial
Development focused primarily on China
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