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The LD50 concept shows how toxicity is measured in preclinical work
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This has made it a focal point in soft-tissue and musculoskeletal recovery research, where durable, well-formed tissue repair is the goal
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Mechanisms (Preclinical Only) Rodent and in vitro studies report modulation of the nitric oxide system via SrcCaveolin1eNOS signaling and context dependent effects on vascular tone
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Dose-dependent FAK and paxillin phosphorylation in rat tendon fibroblasts, promoting cell migration and ECM remodeling without direct effect on basal proliferation
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