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Participants consumed fewer calories per day without being instructed to diet driven by decreased appetite and satiety signaling
Tirzepatide is approved under two brand names: Mounjaro for type 2 diabetes (FDA May 2022) and Zepbound for chronic weight management (November 2023) and moderate-to-severe obstructive sleep apnoea with obesity (December 2024) 28
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Preproglucagon Neurons in the Nucleus of the Solitary Tract Are the Main Source of Brain GLP-1, Mediate Stress-Induced Hypophagia, and Limit Unusually Large Intakes of Food. Diabetes, vol
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