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The table describes weeks one through four at 2.5 mg as an initial gastrointestinal adaptation period with a modest metabolic signal
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Clinical Evidence on Semaglutide and Cardiovascular Risk The SUSTAIN trial series, which followed thousands of patients with type 2 diabetes, demonstrated that semaglutide reduced major adverse cardiovascular events by 26% compared to placebo over three years
Lancet 372, 139144
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