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Starting at 1mg weekly
Patients combining these drugs face elevated risk of hypoglycemic episodes (dangerously low blood sugar) or hyperglycemic spikes, especially during prednisone dose reductions
When prescribing an alternative class of glucose-lowering therapy, clinicians are advised to use medicines across the class evenly to mitigate the potential for further national shortages, the notification added
Results showed a more significant reduction in liver fat composition (LFC) in the tirzepatide 10 and 15 mg group versus the insulin degludec group
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