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Indications for Use As aforementioned, researchers are evaluating tesamorelin for several conditions, including NAFLD, insulin resistance, and obesity
AOD9604 and Energy Balance Research In obese ob/ob and lean C57BL/6J mice treated for 14 days via mini-osmotic pumps, AOD9604 significantly reduced body weight gain in obese mice, associated with increased in vivo fat oxidation and increased plasma glycerol levels as an index of enhanced lipolysis without the hyperglycaemia or reduced insulin secretion associated with intact hGH treatment
Additionally, the treatment altered the levels of certain important molecules within the cells, suggesting changes that could inhibit cancer progression
AOD9604 did not stimulate the production of IGF-1 in any of the systems studied, and elicits its fat-reducing effects without inducing insulin resistance a key pharmacological distinction from intact hGH that makes it a uniquely clean research tool for studying lipolytic mechanisms in isolation
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