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Simultaneous regeneration of full-thickness cartilage and subchondral bone defects in vivo using a three-dimensional scaffold-free autologous construct derived from high-density bone marrow-derived mesenchymal stem cells

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Tissue repair and pain research A 2025 review tracked BPC-157 from tissue regeneration toward pain modulation, collecting reports where the peptide reduced inflammatory signalling and supported nerve and tissue recovery after injury, while stressing that robust human mechanism data are not yet available [5]