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Additionally, elevated homocysteine levels may indicate inefficient biosynthesis of essential proteins, caused by folate metabolism abnormalities
"Rhodiola rosea in stress induced fatiguea double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty." Phytomedicine 7.5 (2000): 365-371
10.1002/jmv.20388 J
The published trials excluded several populations and conditions
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