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Elevated intracellular iron levels facilitate the generation of ROS through Fenton chemistry, subsequently initiating lipid peroxidation reactions ( Compared with other forms of cell death such as apoptosis, necrosis, and autophagy, ferroptosis exhibits distinct molecular mechanisms and biological features ( Table 1 ): (1) Iron Dependence: Ferroptosis is uniquely triggered by elevated intracellular iron levels, differentiating it from other cell death modes

Nat Med 26:845848

I eat a pretty healthy diet

Bellia F, Lanza V, Naletova I, Tomasello B, Ciaffaglione V, Greco V, Sciuto S, Amico P, Inturri R, Vaccaro S, Campagna T, Attanasio F, Tabb G, Rizzarelli E (2023) Copper(II) complexes with carnosine conjugates of hyaluronic acids at different dipeptide loading percentages behave as multiple SOD mimics and stimulate Nrf2 translocation and antioxidant response in in vitro inflammatory model