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Participants were randomly assigned to one of five therapies: exenatide alone, dapagliflozin alone, dual therapy of exenatide and dapagliflozin, combined dapagliflozin and metformin therapy, or the weight-loss medication phentermine/topiramate extended-release
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Patients with a personal or family history of breast cancer should use choline supplementation cautiously, as some observational studies suggest high-dose choline intake correlates with increased breast cancer risk in genetically susceptible populations
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