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The 100mg cohort showed statistically significant reductions in visceral adipose tissue (8.3% vs baseline) and improvements in insulin sensitivity (HOMA-IR reduction of 18.7%), but no hepatotoxicity signals emerged across any dose tier
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[3] For confirmed deficiency with neurological involvement: 1 mg IM on alternate days until no further improvement, then 1 mg every two months urgent initiation is essential to prevent irreversible nerve damage
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