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Of the patients who took semaglutide and then developed NAION, those aged 40 to 64 (HR=3.31), who were female (HR=3.24), who were white (HR=2.34) or who had hypertension (HR=2.42) were more likely to be affected
This approach works particularly well for individuals who have experienced severe GI side effects on previous GLP-1 medications, those with pre-existing digestive conditions, or anyone who prioritizes tolerability over speed of escalation
2 Adherence remains challenging
Some users may not experience any change in their facial appearance at all, while others may notice mild to moderate symptoms
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