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Combinative treatment of -elemene and cetuximab could induce ferroptosis of KRAS-mutant colorectal cancer cells (CRC) by iron-dependent ROS accumulation, GSH depletion, lipid peroxidation, upregulation of HO-1 and transferrin, and downregulation of negative regulatory proteins for ferroptosis (GPX4, SLC7A11, FTH1, glutaminase, and SLC40A1), thus inhibiting tumor growth and lymph node metastases in vivo ( Curcuma zedoaria [Zingiberaceae
In order to protect neurons, heart cells, nephrons from the toxicity of chemotherapy (cisplatin, oxaliplatin, etc.) is prescribed at a dosage of 1200 mg intravenously in saline 50-200 ml 15 minutes before the use of chemotherapy
This is one of the reasons why an empty vile of sterile water contains only a couple of milliliters of liquid
DailyMed prescribing information MRGPRX2 recognition of cationic amphiphilic ligands - Review of the receptors ligand features and role in non-IgE mast-cell activation
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