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We assessed the cleavage activity of X(PC) on this library of 2,880 high-activity substrates (Extended Data Fig
Omzo's brand materials describe tirzepatide as offering "dual-hormone support that targets appetite, blood sugar, and metabolism for deeper, sustained progress." Clinical trials of tirzepatide (the active ingredient in Zepbound and Mounjaro) have shown substantial weight loss outcomes in studied populations, and some trials have shown greater average weight reduction with tirzepatide compared to semaglutide in head-to-head comparisons - though individual responses vary and neither medication is appropriate for all patients
J Diabetes Invest 5:714721
Phase I reactions transform compounds through oxidation, reduction or hydrolysis
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