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They showed that EED deletion in mouse neural stem/progenitor cells by conditional knockout of EED driven by hGFAP-Cre inhibited neurogenesis in vivo , with a strong decrease of neuroblasts and immature neurons (DCX + cells), as well as in vitro , with reduced proliferation of primary neural stem/progenitor cells in neurosphere cultures
Almost no side affects
It also focuses on vascular signaling and inflammatory pathways
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