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Some patients say semaglutide made them feel more anxious or depressed A review of real-world data from healthcare databases and registries is underway
Both medications are GLP-1 agonists, but they have slightly different indications and clinical trial results
10.1186/s12916-025-03901-w BMC Med
Together, they can suppress hunger to the point where people eat 600 to 800 calories per day without intending to, which triggers severe metabolic adaptation, muscle loss, and nutritional deficiencies
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