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GSTs are also involved in the phase I detoxification process such as dehydrochlorination of 1,1,1-Trichloro-2,2-bis( p -chlorophenyl) ethane (DDT) to less toxic 1,l-Dichloro-2,2-bis( p -chlorophenyl) ethylene (DDE) [22, 43, 44]
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CMS has indicated it is collecting utilization data during the program period to inform longer-term policy decisions
As an off-target effect, the metabolomics revealed that histidine supplementation reduced and augmented tumoral concentrations of adenosine monophosphate and tryptophan respectively, metabolites associated with immunosuppressive or immunostimulating potential respectively (Supplementary Fig
