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In the late stages of PD, the key molecular pathogenic mechanisms include the misfolding and aggregation of -synuclein, mitochondrial dysfunction, impaired protein clearance (related to inefficient ubiquitin-proteasome and autophagy-lysosomal systems), neuroinflammation and oxidative stress (57)
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Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2-CT method
It goes to a special area that acts like your bodys appetite control center. There, it sends a strong signal that you are full and satisfied
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