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Importantly, co-treatment with PB2 or Shikonin and sorafenib significantly increases the chemosensitivity of HCC to sorafenib [158, 259]

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Functional Innovative Aspects CLA is a precursor of an antagonist of the arachidonic acid (fatty acid occurring in biological cells membranes and the most abundant precursor of eicosanoids like prostaglandins, tromboxanes and leucotriens)

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