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Normally, repair crews (blood vessels, fibroblasts, macrophages etc) take time to arrive and fix the damage especially in low-traffic areas like tendons and ligaments that dont get much blood flow
Even a highly purified peptide can produce inconsistent experimental results if it is improperly reconstituted, contaminated during handling, or stored outside recommended conditions
Crows feet add another 20 to 30
Dupixent can be left at room temperature up to 77F (25C) for a maximum of 14 days
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