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Samples were subjected to Seahorse analysis (Agilent) as previously described ( 6 cells/mL for the cell lines and 5 10 6 /mL for the primary CLL primary lymphocytes
Originally developed by Eli Lilly, it belongs to a new generation of nutrient-stimulated hormone-based research compounds and has drawn substantial scientific attention for its unique triple-agonist activity
Superoxide dismutase is known to reverse fibrosis, possibly by de-differentiating myofibroblasts back into fibroblasts
No significant protection was observed for the endogenous agonist, GLP-1 (Figure S2)
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