You can read the full article at NeuroSearch is developing a compound called NS-2330, which enhances the activity of dopamine, norepinephrine, and acetylcholine
In myeloid cell lines there was a more differential effect: when quercetin and apigenin were used in combination with each topoisomerase II inhibitor, there was a synergistic/additive decrease in cell proliferation, cell accumulation in G 2 M and S phase of the cell cycle and an increase in apoptosis
In addition, insomnia rats showed changes in oxidative stress levels (decreased expression of antioxidant enzymes SOD, GSG, and CAT, and increased expression of pro-oxidases GSSG, MDA, and LDH) and pathological damage to mitochondria
Age-dependent oxidative stress elevates arginase 1 and uncoupled nitric oxide synthesis in skeletal muscle of aged mice