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The commonly used dietary methionine restriction regimen has been shown to extend life span, delay aging, prevent metabolic diseases, reduce cancer growth, and sensitize cancer cells to chemotherapy and radiation in mice 14,42,43
The peptide's ability to cross the blood-brain barrier and its stability may make this route viable
TR- agonists have demonstrated improvements in liver fat and biomarkers of cardiovascular disease along with significant resolution of NASH, but have not demonstrated a strong anti-fibrotic effect (330)
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