218 Secondary mutations in BRAF, KRAS, NRAS, and MEK1/2 have been widely observed in patients treated with BRAF and MEK inhibitors, restoring ERK signaling and driving therapeutic failure
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I think a lot of companies we're going to see maybe shifting away from this custom approach because they are afraid that the FDA could come in any day and shut them down and say you can't do this anymore. George Ball, Indiana University associate professor of operations and decision technologies, has a different take on the situation