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The X domain represents the first half while the Y domain represents the second half, of the TIM barrel-like structure (Nagano et al., 2002)
Additionally, real-world pharmacovigilance data highlight sensory adverse events (particularly dysgeusia) that appear more frequently in clinical practice than in controlled trials, suggesting under recognition of taste-related disturbances in research settings (159)
The medication may also increase the risk of urinary tract infections, hypoglycemia, severe bacterial infection of the genital area, and fungal infections
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