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A recent systematic review (2025) concluded that liraglutide generally promotes the growth of metabolically beneficial taxa, consistent with improved host metabolic functions ( Akkermansia muciniphila, Lactobacillus , and Bifidobacterium , along with a reduction of obesity-associated genera emerges as a reproducible pattern, highlighting that species-level and functional alterations are more informative than phylum-level shifts ( In human gut microbiota analyses, one study reported increases in Faecalibacterium prausnitzii and Peptostreptococcus anaerobius (Bacillota) , as well as Bacteroides vulgatus (Bacteroidota) and Akkermansia muciniphila (Verrucomicrobiota ) ( Bacteroidota and reduced Bacillota , a microbial profile associated with lower insulin resistance and obesity
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Continuing obesity therapy was tied to more than four times higher odds of 10% or greater weight loss
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