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Clinical trial data including the FLOW trial (NEJM, 2024) and earlier cardiovascular outcome trials such as LEADER and SUSTAIN-6 suggest these agents may offer renoprotective benefits in people with type 2 diabetes and CKD , including reductions in albuminuria and slowing of disease progression

Conclusions Patients taking long-acting GLP-1 RAs such as semaglutide may be at risk of pulmonary aspiration under anesthesia

Remember: your dose may need to go up, but your price won't, keeping treatment accessible as your therapy advances

For these users, the limited effectiveness of drops aligns with their limited ambitions