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Their research demonstrated that SCFA-producing bacteria are reduced in CKD, resulting in lower circulating levels of SCFAs
Bhatta RS, Kumar D, Chhonker YS, Jain GK
Other cautions include: History of pancreatitis or gallbladder disease Certain gastrointestinal disorders Pregnancy or breastfeeding Specific allergy or sensitivity to semaglutide Common side effects can include nausea, vomiting, diarrhea, constipation, abdominal discomfort, and fatigue, especially during dose escalation
For instance, high-sugar or high-fat diets increase Akkermansia , Proteobacteria , and endotoxemia while elevating the Firmicutes/Bacteroidetes ratio and reducing bifidobacteria abundance (Sen et al., 2017)
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