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N Engl J Med 389(12):10691084 Kosiborod MN, Petrie MC, Borlaug BA, Javed B, Davies MJ, Hovingh GK et al (2024) Semaglutide in patients with obesity-related heart failure and type 2 diabetes

However, these effects may come and go at first, since the body is still adjusting to the medication and the starting dose is intentionally low to minimize side effects