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(2022) Methyltransferases: functions and applications, ChemBioChem , 23 , e202200212, Joncquel-Chevalier Curt, M., Voicu, P.-M., Fontaine, M., Dessein, A.-F., Porchet, N., Mention-Mulliez, K., and Vamecq, J

Psoralen (PSR) in conjunction with ultraviolet A (PUVA) treats vitiligo, a depigmenting skin condition, by promoting both tyrosinase activity and melanin production in melanocytes

Doses are then adjusted based on fasting blood glucose readings, typically every 3 to 4 days

There are a number of reasons for the frequent use of this therapy: from a pathophysiological point, the metformin/DPP-4 combination leads to higher GLP-1 concentrations compared to a therapy with a DPP-4 inhibitor alone (75)