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Presented for research literature review only Fallows E et al

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Intracellular production of OH from H 2 O 2 is driven by the Fenton reaction, shown in Reaction 3 (43, 44, 48): As the most reactive known ROS, OH reacts with nearly all intracellular building blocks and macromolecules (amino acids, nucleic acids, phospholipids, sugars, proteins, RNA, DNA, lipids, polysaccharides)

Biomedical Res Therapy 12(8):76217632 Yang G, Lyu L, Wang X, Bao L, Lyu B, Lin Z (2019) Systemic treatment with resveratrol alleviates adjuvant arthritis-interstitial lung disease in rats via modulation of JAK/STAT/RANKL signaling pathway