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Despite the absence of a prolonged anorectic effect, Cagrilintide produced a sustained and significant reduction in body weight in WT mice by 3.4 g after 21 days, while no such effect was observed in KO animals

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This consequence is especially apparent when comparing the impact of different health determinant domains on money spent in billions annually, e.g., behavior has a 38% annual impact (equivalent to USD 260 billion), while medical care has an 11% annual impact (or total USD 3,337 billion) (274)