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PYX-201, a stroma-targeting ADC composed of an anti-EDB+FN antibody conjugated to Auristatin0101, demonstrates strong anti-tumor efficacy across multiple human cancer indications in pre-clinical PDX tumor models
While mild to moderate nausea is expected with tirzepatide, certain symptoms require prompt medical evaluation
The generic debut comes after Novo Nordisk, in 2019, failed to pay a $250 CAD maintenance fee on Canadian patent CA 2601784
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