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Hypoxia increases mitochondrial ROS formation and leads to enhanced infiltration of activated inflammatory cells (71)

Glutathione is composed of three amino acids: cysteine, glutamine, and glycine

It has been shown to counteract NSAID-induced ulcers, esophagitis, and inflammatory bowel conditions like colitis by promoting epithelial integrity, increasing mucosal blood flow, and regulating the gut-brain axis

In recent years, novel regulatory factors of apoptosis, including non-coding RNA, estrogen receptor ER-36, and various circulating proteins, have been identified (121123), expanding our understanding of apoptosis regulatory network