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Dose ranges are often species- and model-dependent, with rodent studies using body-weight-normalized doses (mcg/kg or mg/kg) that may be substantially different from the fixed doses used in primate or pharmacokinetic models
A Phase I/II Study of Combination of Azacitidine, Venetoclax and Pevonedistat in Patients with Newly-Diagnosed Secondary Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) with Hypomethylating Agent (HMA) Failure
That policy was reversed following our involvement and injections were re-instated
