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Many people find they need to take very high doses for a long time to see any difference, which can lead to digestive upset
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All controlled studies referenced below were conducted in cell culture (3T3-L1 adipocytes, primary muscle stem cells) or rodent models (diet-induced obese mice, aged C57BL/6J mice)
Seek Immediate Medical Attention If You Experience: Severe stomach pain that doesnt go away (could be a sign of pancreatitis) Pain in the upper right side of your belly, especially after meals (this could mean gallbladder issues) Signs of dehydration from extreme vomiting or diarrhea (such as dizziness, dry mouth, or dark urine) Swelling in your neck, trouble swallowing, or hoarseness (very rare, but possibly related to thyroid changes) Skin rashes, swelling of the face or lips, or trouble breathing (could be a sign of an allergic reaction) If you experience any of these, dont wait
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